1228677-99-3Relevant academic research and scientific papers
Highly α-selective synthesis of sialyl spirohydantoins by regiospecific domino condensation/O→N acyl migration/N-sialylation of carbodiimides with peracetylated sialic acid
Zhang, Dengyou,Ye, Deju,Feng, Enguang,Wang, Jinfang,Shi, Jianmei,Jiang, Hualiang,Liu, Hong
experimental part, p. 3552 - 3557 (2010/07/04)
Figure presented A novel and efficient process for the synthesis of α-sialyl spirohydantoin analogues via one-pot sequential reaction involving various carbodiimides and peracetylated Neu5Ac is reported. BF 3·Et2O mediating intramolecular N-sialylation with excellent α-selectivity is first demonstrated.
