1228682-74-3

Upstream product

• 477330-46-4 3-phenyl-1-(4-(trifluoromethyl)phenyl)prop-2-yn-1-ol 

Downstream Products

• 1228682-88-9 (E)-acrylaldehyde O-[1-(4-trifluoromethylphenyl)-3-phenylprop-2-yn-1-yl]oxime 
• 1388624-47-2 4-(trifluoromethyl)benzaldehyde O-{3-phenyl-1-[4-(trifluoromethyl)phenyl]prop-2-yn-1-yl}oxime 
• 1388624-68-7 (4E)-1-phenyl-4-[4-(trifluoromethyl)benzylidene]-3-[4-(trifluoromethyl)phenyl]azetidin-2-one 
• 1430095-04-7 (E)-cyclopropanecarbaldehyde O-(3-phenyl-1-(4-(trifluoromethyl)phenyl)prop-2-ynyl)oxime 
• 1430094-95-3 (Z)-cyclopropanecarbaldehyde O-(3-phenyl-1-(4-(trifluoromethyl)phenyl)prop-2-ynyl)oxime 

Relevant academic research and scientific papers

Copper-catalyzed skeletal rearrangement of o -propargylic aryloximes into four-membered cyclic nitrones - Chirality transfer and mechanistic insight

Copper-catalyzed skeletal rearrangement of O-propargylic aryloximes (E)-1 were carried out to afford the corresponding four-membered cyclic nitrones 2 in good to excellent yields. The optimal reactions conditions of the highly regioselective reactions inv

Copper-catalyzed tandem [2,3]-Rearrangement and 6π-3-Azatriene electrocyclization in (E) -O -Propargylic α,β-Unsaturated oximes

Cu-catalyzed cyclizations of (E)-O-propargylic oximes of α,β-unsaturated aldehydes were successfully carried out to afford the corresponding pyridine oxides in good to high yields. As an example, (E)-acrylaldehyde O-1,3-diphenylprop-2-ynyl oxime (1b) was reacted for 5 h in the presence of CuBr(PPh3)3 (10 mol %) and PPh3 (10 mol %) in DMSO at 120 C to afford 3-benzyl-2-phenylpyridine-N-oxide (2b) in 84% yield. In this case, the reaction proceeded via Cu-catalyzed propargyl oxime-allenyl nitrone rearrangement followed by 6-3-azatriene electrocyclization.