1228699-87-3Relevant academic research and scientific papers
Synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds
Liu, Jiyan,Wang, Wei,Wang, Rui,Gu, Lijun
, p. 559 - 562 (2015)
It was found for the first time that Cs2CO3 serves as highly efficient catalyst for the direct hydroxylation reactions of phosphonates under mild conditions. This reaction provides an efficient approach to quaternary α-hydroxy phosph
The catalytic aerobic synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds
Gu, Lijun,Jin, Cheng,Zhang, Hongtao
supporting information, p. 1579 - 1582 (2015/03/18)
A highly efficient Cu-catalyzed direct hydroxylation of phosphonate compounds has been developed. This transformation provides a powerful method for the synthesis of quaternary α-hydroxy phosphonates in good yields. The direct transformation process, regiospecific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.
C-H hydroxylation of phosphonates with oxygen in [bmIm]OH to produce quaternary α-hydroxy phosphonates
Li, Xiangguang,Jin, Cheng,Gu, Lijun
, p. 2443 - 2447 (2015/05/04)
A highly efficient and mild [bmIm]OH-catalyzed α-hydroxylation of phosphonates using O2 as the oxygen source is described. The employment of ionic liquid under mild reaction conditions makes this transformation green and practical. Especially, this reaction provided a novel and convenient methodology for the construction of quaternary α-hydroxy phosphonates.
Highly efficient synthesis of quaternary α-hydroxy phosphonates via lewis acid-catalyzed hydrophosphonylation of ketones
Zhou, Xin,Liu, Yanling,Chang, Lu,Zhao, Jiannan,Shang, Deju,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information; experimental part, p. 2567 - 2572 (2009/12/27)
A Lewis acid catalyst has been first applied to the hydrophosphonylation of ketones, giving the corresponding quaternary a-hydroxy phosphonates in high yields (up to 98%). The present method was highly tolerable for functionalized ketones. Moreover, the f
