122872-27-9Relevant academic research and scientific papers
Camphor-based α-bromo ketones for the asymmetric Darzens reaction
Palomo,Oiarbide,Sharma,Gonzalez-Rego,Linden,Garcia,Gonzalez
, p. 9007 - 9012 (2000)
(1R)-2endo-Bromoacetyl-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol (endo-2-bromoacetylisoborneol)4 and its trimethylsilyl ether 3 are presented as efficient reagents for the asymmetric Darzens reaction. From the α,β-epoxy ketone adducts the chiral inductor camphor is removed, by treatment with ceric(IV) ammonium nitrate, to yield the corresponding epoxy acids which are isolated as their dicyclohexylammonium salts.
