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Usage

Uses

Used in Pharmaceutical Research:
(2R,2'R,3R,3'R) MeO-BIBOP is used as a ligand for opioid receptors in pharmaceutical research. Its unique structure and potential pharmacological activity make it a promising candidate for the development of new medications targeting opioid receptors.
Used in Medicinal Chemistry:
(2R,2'R,3R,3'R) MeO-BIBOP is used in medicinal chemistry for the exploration of its potential medicinal applications. Its complex molecular structure and multiple stereocenters provide opportunities for the design and synthesis of new compounds with therapeutic potential.
Used in Drug Discovery:
(2R,2'R,3R,3'R) MeO-BIBOP is used in drug discovery for the identification and development of new pharmaceutical agents. Its potential as an opioid receptor ligand and its unique structure make it a valuable tool in the search for novel therapeutic agents.

Upstream product

• 1202033-03-1 (R)-3-tert-butyl-4-methoxy-2,3-dihydrobenzo[d][1,3]oxaphosphole oxide 
• 1215081-21-2 (S)-3-(tert-butyl)-4-methoxy-2,3-dihydrobenzo[d][1,3]oxaphosphole 3-oxide 

Relevant academic research and scientific papers

The P-chiral phosphane ligand (MeO-BIBOP) for efficient and practical large-scale Rh-catalyzed asymmetric hydrogenation of N-acetyl enamides with high TONs

A highly electron-rich P-chiral bis(trialkylphosphane) ligand MeO-BIBOP (1) was efficiently synthesized on large scale. The MeO-BIBOP-rhodium complex exhibited remarkably high reactivities (up to 200,000 TON) for the hydrogenation of N-acetyl enamides to

Enantioselective rhodium-catalyzed addition of arylboronic acids to trifluoromethyl ketones

A new C2-symmetrical, chiral bisphosphorus ligand proved to be efficient for the rhodium-catalyzed nucleophilic addition of arylboronic acids to trifluoromethyl ketones, providing a series of chiral trifluoromethyl- substituted tertiary alcohols in high yields (up to 93%) and excellent enantioselectivities (>99%). Copyright