122888-41-9

Upstream product

• 122888-38-4 (3E)-1-chloro-3-methyl-4-phenyl-3-buten-2-one 
• 87066-85-1 1-acetyl-2-methoxy-1,2-dihydro-3H-indol-3-one 
• 122888-40-8 (E)-3-methyl-2-oxo-4-phenylbut-3-enylidene(triphenyl)phosphorane 

Downstream Products

• 152714-98-2 1-acetyl-2-methoxy-3-<(1Z,3E)-3-methyl-4-phenyl-2-(trimethylsiloxy)buta-1,3-dienyl>indole 
• 122888-42-0 1-[2-Methoxy-3-((1E,3E)-3-methyl-4-phenyl-2-trimethylsilanyloxy-buta-1,3-dienyl)-indol-1-yl]-ethanone 
• 152714-99-3 1-(3-Methoxy-2-methyl-1-phenyl-carbazol-9-yl)-ethanone 
• 122888-43-1 9-acetyl-2-methyl-1-phenyl-3-(trimethylsiloxy)-9H-carbazole 
• 122888-44-2 9-acetyl-2-methyl-1-phenyl-9H-carbazol-3-ol 
• 123719-47-1 3-hydroxy-2-methyl-1-phenyl-9H-carbazole 
• 74364-11-7 3-methoxy-2-methyl-1-phenyl-9H-carbazole 

Relevant academic research and scientific papers

A New Efficient Synthesis of the 3-Methoxycarbazole Alkaloid Hyellazole

A short synthesis of hyellazole (1) based on a new method of benzannelation of indoles which involves cyclization of 3-buta-1,3-dienylindole (6) is described.

New Approach to 3-Oxygenated Carbazoles. Synthesis of Hyellazole and 4-Deoxycarbazomycin B

3-Oxygenated carbazoles are prepared in 4 steps from 1-acetyl-2-methoxy-1,2-dihydroindol-3-one 6 by Wittig reaction with phosphonium ylides 10 to afford the 3-alkylindoles 11, followed by silylation to the silyl enol ethers 12.Electrocyclic reaction of the enol ethers 12 followed by desilylation give the 3-hydroxycarbazoles 15.The carbazoles 15a,b were converted into the carbazole alkaloid hyellazole 1 and 4-deoxycarbazomycin B 2a, respectively.