122895-15-2Relevant academic research and scientific papers
A Stereoselective Synthesis of Trisubstituted Alkenes. Part 2. The Nickel-catalysed Coupling of Grignard Reagents with 5-Alkyl-3,4-dihydro-2H-pyrans and Acyclic Enol Ethers
Ashworth, Philip A.,Dixon, Nicholas J.,Kocienski, Philip J.,Wadman, Sjoerd N.
, p. 3431 - 3438 (1992)
The Ni(0)-catalysed coupling of Grignard reagents devoid of β-hydrogens with 6-alkyl-3,4-dihydro-2H-pyrans and acyclic enol ethers is highly stereoselective and gives trisubstituted alkenes with retention of configuration.The reaction was applied to synth
A Stereoselective Synthesis of Tri-substituted Alkenes. The Nickel-Catalysed Coupling of Grignard Reagents with 6-Alkyl-3,4-dihydro-2H-pyrans.
Kocienski, Philip,Dixon, Nicholas J.,Wadman, Sjoerd
, p. 2353 - 2356 (2007/10/02)
The nickel-catalysed coupling of certain Grignard reagents with 6-alkyl-3,4-dihydro-2H-pyrans is highly stereoselective and gives tri-substituted alkenes with retention of configuration.The method was applied to the synthesis of (E)-3-Acetoxy-7-methyl-6-nonene, the aggregation pheromone of the square-necked grain beetle.
