1229009-59-9

Basic information

• Product Name: 1-[(3-(4-chlorophenyl)-1,4-diphenyl-1H-pyrazol-5-yl)]carbonyl-2,3-dihydro-1H-benzimidazole-2-thione
• CAS NO: 1229009-59-9
• Molecular Weight: 507.015
• Mol File: 1229009-59-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(3-(4-chlorophenyl)-1,4-diphenyl-1H-pyrazol-5-yl)]carbonyl-2,3-dihydro-1H-benzimidazole-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(3-(4-chlorophenyl)-1,4-diphenyl-1H-pyrazol-5-yl)]carbonyl-2,3-dihydro-1H-benzimidazole-2-thione(1229009-59-9)
• EPA Substance Registry System: 1-[(3-(4-chlorophenyl)-1,4-diphenyl-1H-pyrazol-5-yl)]carbonyl-2,3-dihydro-1H-benzimidazole-2-thione(1229009-59-9)

Safety Data

• Hazardous Substances Data: 1229009-59-9(Hazardous Substances Data)

Upstream product

• 15424-14-3 N-phenylbenzohydrazonoyl chloride 
• 23983-06-4 2-(4-chlorobenzylidene)thiazolo<3,2-a>benzimidazol-3(2H)-one 

Relevant articles and documents

Microwave-assisted synthesis and in-vitro anti-tumor activity of 1,3,4-triaryl-5-N-arylpyrazole-carboxamides

Regioselective 1,3-dipolar cycloaddition of nitrilimines with 5-arylidene-2-arylimino-4-thiazolidinones and with 2-(4-arylidene)thiazolo[3,2-a]benzimidazol-3(2H)-ones afforded the corresponding 1,3,4-triaryl-5-N-arylpyrazole-carboxamides and pyrazolylbenzimidazoles. All reactions were carried out under conventional thermal heating and/or microwave irradiation. Both the pyrazole-5-carboxamides and pyrazolylbenzimidazoles were examined for their in-vitro anti-tumor activities against two tumor cell lines, Hep-2 and colon CaCo-2. Most of the obtained compounds exhibited significant activity against CaCo-2 and Hep-2 cell lines.