122903-58-6

Basic information

• Product Name: 2-(3,5-Dimethoxyphenyl)-2-butanol
• CAS NO: 122903-58-6
• Molecular Weight: 210.273
• Mol File: 122903-58-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3,5-Dimethoxyphenyl)-2-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-Dimethoxyphenyl)-2-butanol(122903-58-6)
• EPA Substance Registry System: 2-(3,5-Dimethoxyphenyl)-2-butanol(122903-58-6)

Safety Data

• Hazardous Substances Data: 122903-58-6(Hazardous Substances Data)

Upstream product

• 39151-19-4 1-(3,5-dimethoxyphenyl)ethan-1-one 
• 925-90-6 ethylmagnesium bromide 
• 2386-64-3 ethylmagnesium chloride 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 14950-55-1 rac-1-(3,5-dimethoxyphenyl)ethan-1-ol 
• 122903-50-8 3-(3,5-Dimethoxyphenyl)-2-butyl methanesulfonate 

Relevant articles and documents

Access to "friedel-Crafts-Restricted" tert -alkyl aromatics by activation/methylation of tertiary benzylic alcohols

Herein we describe a two-step protocol to prepare m-tert-alkylbenzenes. The appropriate tertiary benzylic alcohols are activated with SOCl2 or concentrated HCl and then treated with trimethylaluminum, affording the desired products in 68-97% yields (22 examples). This reaction sequence is successful in the presence of a variety of functional groups, including acid-sensitive and Lewis-basic groups. In addition to t-Bu groups, 1,1-dimethylpropyl and 1-ethyl-1-methylpropyl groups can also be installed using this method.