1229439-68-2Relevant academic research and scientific papers
Catalytic enantioselective addition of sodium bisulfite to chalcones
Moccia, Maria,Fini, Francesco,Scagnetti, Michela,Adamo, Mauro F. A.
supporting information; experimental part, p. 6893 - 6895 (2011/08/06)
At last! The addition of bisulfite to olefins, discovered over a century ago, remains the most straightforward approach to aliphatic sulfonic acids. A catalytic enantioselective procedure has now been realized that employs a bifunctional aminothiourea catalyst (see picture). Sulfonic acids were obtained from chalcones in high yields and high enantioselectivity and in both configurations. Copyright
