1229454-63-0Relevant academic research and scientific papers
A reliable synthesis of 3-amino-5-alkyl and 5-amino-3-alkyl isoxazoles
Johnson, Leland,Powers, James,Ma, Fupeng,Jendza, Keith,Wang, Bing,Meredith, Erik,Mainolfi, Nello
, p. 171 - 173 (2013/03/13)
A reliable procedure that can be used to access a wide range of 3-amino-5-alkyl and 5-amino-3-alkyl isoxazoles was developed. Reaction temperature and pH were key factors that determined the regioselectivity of the two reactions.
Pyridyloxyindoles Inhibitors of VEGF-R2 and Use Thereof for Treatment of Disease
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Page/Page column 61, (2010/06/22)
The invention relates to novel organic compounds of formula (I), and their use in the treatment of the animal or human body, to pharmaceutical compositions comprising a compound of formula I and to the use of a compound of formula I for the preparation of pharmaceutical compositions for use in the treatment of protein kinase dependent diseases, especially of proliferative diseases, such as in the treatment of tumour diseases and ocular neovascular diseases.
