1229516-60-2Relevant academic research and scientific papers
Directed lithiation of N -benzenesulfonyl-3-bromopyrrole. Electrophile-controlled regioselective functionalization via dynamic equilibrium between C-2 and C-5 lithio species
Fukuda, Tsutomu,Ohta, Takeshi,Sudo, Ei-Ichi,Iwao, Masatomo
supporting information; experimental part, p. 2734 - 2737 (2010/08/19)
(Figure presented) Directed lithiation of N-benzenesulfonyl-3-bromopyrrole (1) with LDA in THF at -78 °C generated C-2 lithio species 3 selectively. Reactions of 3 with reactive electrophiles produced the corresponding 2-functionalized pyrroles 4. On the
