122955-82-2Relevant academic research and scientific papers
RADIOLABELED SUGARS FOR IMAGING OF FUNGAL INFECTIONS
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Page/Page column 39, (2021/02/12)
Disclosed herein are compounds having a structure according to Formula I and optionally Formula IV. Formula I Formula IV. The compounds may be radiolabeled compounds useful for diagnosis and/or imaging fungal infections. In such embodiments, at least one substituent is a radionuclide, such as 18F. Also disclosed are precursor compounds according to Formula I and/or IV that are useful for making the radiolabeled compounds. In such embodiments, the precursor compound comprises at least one leaving group suitable for introducing a radionuclide, such as 18F, at a desired position. Also disclosed are methods for making and using the compounds, including embodiments of a method for imaging and/or diagnosing a fungal infection in a subject.
Synthesis and characterization of 6-O-β-lactosyl-α,β-D-mannopyranoses and 2,6-di-O-β-lactosyl-α,β-D-mannopyranoses. Synthesis and Binding of D-Galactose-terminated Ligands to Human and Rabbit Asialoglycoprotein Receptor. Part IV.
Hronowski, Lucjan J. J.,Szarek, Walter A.,Hay, George W.,Ison, Edward R.,Krebs, Anita,Depew, William T.
, p. 51 - 69 (2007/10/02)
The reaction of 2,3,6,2',3',4',6'-hepta-O-acetyl-α-lactosyl bromide (4) and benzyl 3,4-di-O-benzyl-α-D-mannopyranoside (3) in the presence of mercury(II) cyanide in benzene-nitromethane produced benzyl 3,4-di-O-benzyl-2,6-bis-O-(2,3,6,2',3',4',6'-hepta-O-
