1229584-17-1

Basic information

• Product Name: 1H-IMidazole, 2-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
• Synonyms: 1H-IMidazole, 2-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-;(4-(1H-IMIDAZOL-2-YL)PHENYL)BORONIC ACID PINACOL ESTER
• CAS NO: 1229584-17-1
• Molecular Formula: C₁₅H₁₉BN₂O₂
• Molecular Weight: 270.13456
• Mol File: 1229584-17-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1H-IMidazole, 2-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-IMidazole, 2-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-(1229584-17-1)
• EPA Substance Registry System: 1H-IMidazole, 2-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-(1229584-17-1)

Safety Data

• Hazardous Substances Data: 1229584-17-1(Hazardous Substances Data)

Usage

General Description

1H-Imidazole, 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]- is a chemical compound with a complex and lengthy name. It contains an imidazole ring and a phenyl group that is substituted with a boron-containing compound. The compound has potential applications in organic synthesis and medicinal chemistry, as boron-containing compounds are often used as reagents in chemical reactions. Overall, this compound has potential in various chemical and pharmaceutical applications due to its unique structure and reactivity.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 176961-53-8 2-(4-bromophenyl)-1H-imidazole 

Downstream Products

• 1229583-68-9 3-[4-(1H-imidazol-2-yl)-phenyl]-5-(3,4,5-trimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine 
• 1257298-58-0 4-{[4-(difluoromethyl)piperidin-1-yl]carbonyl}-7-[4-(1H-imidazol-2-yl)phenyl]-2,3,4,5-tetrahydro-1,4-benzoxazepine 

Relevant articles and documents

HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE

This invention relates to novel compounds and pharmaceutical compositions comprising. Compounds of the invention useful as modulators of Rho-associated protein kinase (ROCK), for example ROCK1 and/or ROCK2 inhibitors. Methods of treatment employing the compounds are also contemplated by the present invention. The compounds of the invention are useful in treating ROCK mediated diseases.

BICYCLIC HETEROARYL KINASE INHIBITORS AND METHODS OF USE

Provided are compounds having an inhibitory effect on kinases including Mixed Lineage Kinases. Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders that comprise the inhibition of Mixed Lineage Kinases.

MLK INHIBITORS AND METHODS OF USE

Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases.