1229604-32-3Relevant academic research and scientific papers
Gold-catalyzed cascade cyclization-oxidative alkynylation of allenoates
Hopkinson, Matthew N.,Ross, Jonathan E.,Giuffredi, Guy T.,Gee, Antony D.,Gouverneur, Veronique
supporting information; experimental part, p. 4904 - 4907 (2011/02/23)
A gold(I)-catalyzed cascade cyclization-oxidative cross-coupling process has been applied to prepare β-alkynyl-γ-butenolides directly from allenoates and various terminal alkynes. Following an initial gold-catalyzed C-O bond forming allenoate cyclization, a mechanism based on a Au I/AuIII redox cycle has been proposed with Selectfluor acting as the external oxidant.
