1229620-77-2Relevant academic research and scientific papers
Enantioselective synthesis of (E)-δ-Stannyl homoallylic alcohols via aldehyde allylboration using α-Stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift
Chen, Ming,Ess, Daniel H.,Roush, William R.
, p. 7881 - 7883 (2010/08/04)
A highly enantioselective synthesis of (E)-δ-stannyl homoallylic alcohols 4 via aldehyde allylboration reactions of the double-chiral allylborane reagent 2a is reported. Allylborane 2a was generated from the hydroboration of commercially available allenylstannane 1 with (dIpc)2BH at -40 to -20 C followed by a kinetically controlled and highly diastereoselective 1,3-boratropic shift in intermediate 3a.
