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1229623-10-2

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  • 3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(2R)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-

    Cas No: 1229623-10-2

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1229623-10-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1229623-10-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,9,6,2 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1229623-10:
(9*1)+(8*2)+(7*2)+(6*9)+(5*6)+(4*2)+(3*3)+(2*1)+(1*0)=142
142 % 10 = 2
So 1229623-10-2 is a valid CAS Registry Number.

1229623-10-2Relevant articles and documents

Synthesis and characterization of sitafloxacin

Liu, Yu,Liu, Lianxin,Shi, Guangxia

, p. 7049 - 7051 (2014)

The convenient protocol for the synthesis of sitafloxacin is described. Reaction of ethyl 3-(3-choloro-2,4,5-trifluorophenyl)-3-oxopropanoate with triethylorthoformate and (1R,2S)-(-)-cis-1,2 fluorine cyclopropane amino-p-toluene sulfonic acid salt by condensation under sodium hydrogen condition. The reaction mixture take place hydrolysis of ester in hydrochloric acid solution. Subsequence reacted with (S)-N[(oxoboryl) methylene] -5-azaspiro[2,4]heptan-7-amine by condensation. In the end taken off the protection group gives sitafloxacin and total conversion about 52-65%. The structure of sitafloxacin was characterized by 1H NMR, 13C NMR, IR, MS and elemental analysis.

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