1229645-87-7Relevant academic research and scientific papers
Novel cytochrome P450-mediated ring opening of the 1,3,4-oxadiazole in setileuton, a 5-lipoxygenase inhibitor
Maciolek, Cheri M.,Ma, Bennett,Menzel, Karsten,Laliberte, Sebastien,Bateman, Kevin,Krolikowski, Paul,Gibson, Christoper R.
experimental part, p. 763 - 770 (2012/05/20)
Setileuton [4-(4-fluorophenyl)-7-[({5-[(1S)-1-hydroxy-1-(trifluoromethyl) propyl]-1,3,4-oxadiazol-2-yl}amino)methyl]-2H-1-benzopyran- 2-one] is a selective inhibitor of the 5-lipoxygenase enzyme, which is under investigation for the treatment of asthma an
