1229648-41-2

Basic information

• Product Name: 10(R)-(tert-butyldiphenylsilanyloxy)-8(R)-methoxy-6(S)-methyltridec-1-en-4(R)-ol
• CAS NO: 1229648-41-2
• Molecular Weight: 496.806
• Mol File: 1229648-41-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 10(R)-(tert-butyldiphenylsilanyloxy)-8(R)-methoxy-6(S)-methyltridec-1-en-4(R)-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 10(R)-(tert-butyldiphenylsilanyloxy)-8(R)-methoxy-6(S)-methyltridec-1-en-4(R)-ol(1229648-41-2)
• EPA Substance Registry System: 10(R)-(tert-butyldiphenylsilanyloxy)-8(R)-methoxy-6(S)-methyltridec-1-en-4(R)-ol(1229648-41-2)

Safety Data

• Hazardous Substances Data: 1229648-41-2(Hazardous Substances Data)

Upstream product

• 1229648-54-7 7(R)-(tert-butyldiphenylsilanyloxy)-5(R)-methoxy-3(R)-methyldecanal 
• 106356-53-0 B-allyldiisopinocampheylborane 

Relevant articles and documents

Formal synthesis of (-)-Neopeltolide featuring a highly stereoselective oxocarbenium formation/reduction sequence

The formal synthesis of the unnatural (-)-neopeltolide core is discussed in detail. Efficient application of the Evans protocol for the synthesis of 1,3-syn-diols via an intramolecular hetero-Michael addition followed by reductive deprotection of the resulting benzylidene acetal allowed for swift access to the δ-lactone. Central to the synthetic approach is a tandem nucleophilic addition-diastereoselective axial reduction of an in situ generated oxocarbenium cation to assemble the β-C-glycoside moiety of the neopeltolide core.