122971-78-2Relevant academic research and scientific papers
Phospholipase-A2-mediated stereoselective synthesis of (R)-1-O-alkylglycero-3-phosphate and alkyl-acyl analogues: Application for synthesis of radiolabelled biosynthetic precursors of cell surface glycoconjugates of Leishmania donovani
Sahai, Parmeshwari,Vishwakarma, Ram A.
, p. 1845 - 1849 (2007/10/03)
Stereoselective syntheses of (R)-1-O-alkylglycero-3-phosphate and alkyl-acyl analogues have been achieved using glycerol as starting material by an efficient application of Phospholipase-A2 enzyme from Naja mocambique mocambique. This synthetic strategy allows a high yielding preparation of radiolabelled [14C] and chirally pure biosynthetic precursors of GIPLs and LPG cell surface molecules of promastigote and amastigote forms of the protozoan parasite Leishmania donovani.
