1229755-30-9

Basic information

• Product Name: 4-bromophenyl N-tert-butylmaleamate
• Synonyms: 4-bromophenyl N-tert-butylmaleamate
• CAS NO: 1229755-30-9
• Molecular Weight: 326.19
• Mol File: 1229755-30-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromophenyl N-tert-butylmaleamate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromophenyl N-tert-butylmaleamate(1229755-30-9)
• EPA Substance Registry System: 4-bromophenyl N-tert-butylmaleamate(1229755-30-9)

Safety Data

• Hazardous Substances Data: 1229755-30-9(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 32350-46-2 (Z)-4-(tert-butylamino)-4-oxo-2-butenoic acid 

Relevant articles and documents

Terification of maleamic acids without double bond isomerization

Activation of the carboxylic acid group of a maleamic acid by treatment with an arenesulfonyl chloride followed by addition of an alcohol affords a fumaramate or a maleamate, depending on the reaction conditions. The E isomer is obtained when the acid is treated with nearly equimolar amounts of 2,4,6-triisopropylbenzenesulfonyl chloride and an alcohol in pyridine. Replacement of pyridine by 2-picoline and use of a larger excess of activating agent (mesitylenesulfonyl chloride) and alcohol affords the Z isomer. In both cases, high diastereomeric excesses and yields are achieved.