122983-01-1

Upstream product

• 122982-84-7 1,1,1-Trifluoro-2-methyl-benzylamino-5-phenyl-2-pentene 
• 1415585-64-6 (E)-(5,5,5-trifluoropent-3-en-1-yl)benzene 
• 68464-36-8 N-benzyl-2,2,2,-trifluoro-N-methylacetamide 
• 39110-26-4 (triphenylphosphonio)-3-phenyl-1-propanide 
• 122982-91-6 1,1,1-Trifluoro-2-methylbenzylamino-5-phenyl-2-pentene hydrochloride 

Relevant academic research and scientific papers

Synthesis of α-Trifluoromethylamines by Cu-Catalyzed Regio- and Enantioselective Hydroamination of 1-Trifluoromethylalkenes

A copper-catalyzed regioselective net hydroamination of 1-trifluoromethylalkenes with hydrosilanes and hydroxylamines has been developed. The judicious choice of ligand and additive suppresses the conceivable but undesired β-F elimination of an α-CF3

A New Synthesis of 1-(Trifluoromethyl)enamines and 1-(Trifluoromethyl)alkylamines

Several 1-(trifluoromethyl)enamines were prepared by heating trifluoroacetamides with alkylidenetriphenylphosphoranes in THF or benzene.The product enamines can be reduced (H2, Pd/C) to 1-(trifluoromethyl)alkylamines.