1229909-94-7Relevant academic research and scientific papers
Microwave-assisted expeditious approach towards benzimidazole acrylonitrile derivatives exploring a new silica supported SBPTS catalyst
Ahmad, Faheem,Parveen, Mehtab
, p. 14602 - 14611 (2018)
The present study reports a simple, highly efficient and green approach for the synthesis of a series of benzimidazole-acrylonitrile derivatives 3(a-l). The synthetic methodology involves a microwave-assisted reaction exploring novel silica-supported SBPTS as a heterogeneous, proficient and reusable catalyst resulting in excellent yields. The reaction transformation presumably occurs via a Knoevenagel condensation. The significant features of the present protocol includes a simple operational procedure, shorter reaction times, mild reaction conditions, economic viability, high yield of products and compatibility with a range of functional groups (electron donating/electron withdrawing).
Benzimidazole derivatives related to 2,3-acrylonitriles, benzimidazo[1,2-a]quinolines and fluorenes: Synthesis, antitumor evaluation in vitro and crystal structure determination
Hranjec, Marijana,Pavlovi?, Gordana,Marjanovi?, Marko,Kralj, Marijeta,Karminski-Zamola, Grace
experimental part, p. 2405 - 2417 (2010/07/05)
A synthesis and biological evaluation of new benzimidazole derivatives, related to 2,3-disubstituted acrylonitriles, benzimidazo[1,2-a]quinoline-6-carbonitriles and heteroaromatic fluorenes was described. The molecular and crystal structures of three comp
