1229936-57-5

Basic information

• Product Name: 3-(2-bromocyclopent-1-enyl)-2-methyl-5-phenylthiophene
• Synonyms: 3-(2-bromocyclopent-1-enyl)-2-methyl-5-phenylthiophene
• CAS NO: 1229936-57-5
• Molecular Weight: 319.265
• Mol File: 1229936-57-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(2-bromocyclopent-1-enyl)-2-methyl-5-phenylthiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-bromocyclopent-1-enyl)-2-methyl-5-phenylthiophene(1229936-57-5)
• EPA Substance Registry System: 3-(2-bromocyclopent-1-enyl)-2-methyl-5-phenylthiophene(1229936-57-5)

Safety Data

• Hazardous Substances Data: 1229936-57-5(Hazardous Substances Data)

Upstream product

• 29421-73-6 3,5-dibromo-2-methylthiophene 
• 554-14-3 2-Methylthiophene 
• 154566-69-5 3-bromo-2-methylthiophene-5-boronic acid 
• 75415-78-0 1,2-dibromocyclopentene 
• 1263307-42-1 2-methyl-5-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 
• 61285-25-4 3-bromo-2-methyl-5-phenylthiophene 

Downstream Products

• 1229936-89-3 (2R,3S,5R)-5-(4-amino-6-methyl-5-(2-(2-methyl-5-phenylthiophen-3-yl)cyclopent-1-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 
• 1229936-73-5 4,4,5,5-tetramethyl-2-(2-(2-methyl-5-phenylthiophen-3-yl)cyclopent-1-enyl)-1,3,2-dioxaborolane 

Relevant articles and documents

Optochemical control of transcription by the use of 7-deaza-adenosine-based diarylethenes

Out of nine different 7-deaza-adenosine diarylethenes, we identified a high-performance photoswitch, suitable for the synthesis of photochromic DNA. By using solid phase synthesis, a photoresponsive T7 promotor was generated which allowed reversibly modulating the rate of enzymatic RNA synthesisin vitro.

The role of alkyl substituents in deazaadenine-based diarylethene photoswitches

Diarylethenes are an important class of reversible photoswitches and often claimed to require two alkyl substituents at the carbon atoms between which the bond is formed or broken in the electrocyclic rearrangement. Here we probe this claim by the synthesis and characterization of four pairs of deazaadenine-based diarylethene photoswitches with either one or two methyl groups at these positions. Depending on the substitution pattern, diarylethenes with one alkyl group can exhibit significant photochromism, but they generally show poor stability towards extended UV irradiation, low thermal stability, and decreased fatigue resistance. The results obtained provide an important direction for the design of new efficient DNA photoswitches for the application in bionanotechnology and synthetic biology.