1230-77-9

Basic information

• Product Name: 3-[4-(dimethylamino)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one
• Synonyms: 4-dimethylamino-4'-methoxychalcone
• CAS NO: 1230-77-9
• Molecular Formula: C₁₈H₁₉NO₂
• Molecular Weight: 281.349
• Mol File: 1230-77-9.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 460.4°C at 760 mmHg
• Flash Point: 232.2°C
• Density: 1.117g/cm³
• Vapor Pressure: 1.17E-08mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 3-[4-(dimethylamino)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(dimethylamino)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one(1230-77-9)
• EPA Substance Registry System: 3-[4-(dimethylamino)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one(1230-77-9)

Safety Data

• Hazardous Substances Data: 1230-77-9(Hazardous Substances Data)

Usage

Backbone Structure

1-(4-methoxyphenyl)prop-2-en-1-one

Functional Groups

4-(dimethylamino)phenyl group
Structure: -N(CH3)2 attached at the third position
Functional Significance: Common in drugs and biologically active molecules, suggests potential pharmacological or biological activity
4-methoxyphenyl group
Structure: -OCH3 attached
Functional Significance: Modulates properties of compounds it's attached to, may contribute to biological or pharmacological activity

Biological/Pharmacological Activity

Likely to exhibit some level of activity in these areas due to the presence of functional groups commonly associated with such activity.

Potential for Investigation

Could be of interest for further research and investigation in biological and pharmacological contexts.

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 1200715-81-6 4-(6-(4-methoxyphenyl)-2-phenylpyrimidin-4-yl)-N,N-dimethylaniline 
• 1550138-73-2 C₃₈H₃₆BF₂N₅O₂ 
• 1550059-95-4 C₁₉H₂₂N₂O₄ 
• 1197386-09-6 2-(p-tolylthio)-4-(4-(dimethylamino)phenyl)-6-(4-methoxyphenyl)pyridine-3-carbonitrile 
• 1262326-36-2 3-(4-methoxyphenyl)-5-(4-dimethylaminophenyl)-2-pyrazoline 
• 75573-14-7 {4-[2-(4-Methoxy-phenyl)-6-p-tolyl-pyridin-4-yl]-phenyl}-dimethyl-amine 

Relevant articles and documents

Electrosynthesis and characterization of a new semi-conducting oligomer deriving from a disubstituted chalcone: 4-dimethylamino -4′-methoxychalcone

An oligo phenylene vinylene was electrosynthesized by the anodic oxidation of the 4-dimethylamino-4′-methoxychalcone (DMAMC) at a constant potential in nitromethane on a platinum electrode. 1H and 13C NMR, FTIR and UV spectroscopy, c

Pyrazoline analogs as potential anticancer agents and their apoptosis, molecular docking, MD simulation, DNA binding and antioxidant studies

N-formyl pyrazoline derivatives (3a–3l) were designed and synthesized via Michael addition reaction through cyclization of chalcones with hydrazine hydrate in presence of formic acid. The structural elucidation of N-formyl pyrazoline derivatives was carri

Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 i