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123002-38-0

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123002-38-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 123002-38-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,0,0 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 123002-38:
(8*1)+(7*2)+(6*3)+(5*0)+(4*0)+(3*2)+(2*3)+(1*8)=60
60 % 10 = 0
So 123002-38-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N6O4S/c11-10-14-7-4(8(15-10)21-12)13-2-16(7)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1,12H2,(H2,11,14,15)/t3-,5-,6-,9-/m1/s1

123002-38-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(Aminosulfanyl)-9-(β-D-ribofuranosyl)-9H-purin-2-amine

1.2 Other means of identification

Product number -
Other names 2-aminoebulariene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123002-38-0 SDS

123002-38-0Upstream product

123002-38-0Relevant articles and documents

Synthesis and Antitumor Evaluation in Mice of Certain 7-Deazapurine (Pyrrolopyrimidine) and 3-Deazapurine (Imidazopyridine) Nucleosides Structurally Related to Sulfenosine, Sulfinosine, and Sulfonosine

Ramasamy, Kandasamy,Imamura, Nobutaka,Hanna, Naeem B.,Finch, Rick A.,Avery, Thomas L.,et al.

, p. 1220 - 1225 (1990)

7-Deaza (pyrrolopyrimidine) and 3-deaza (imidazopyridine congeners of sulfenosine (5a and 9), sulfinosine (6a and 10), and sulfonosine (7a) have been prepared and evaluated for their antileukemic activity in mice.Amination of 2-amino-7-β-D-ribofuranosylpyrrolopyrimidine-4(3H)-thione (4a) and its 2'-deoxy analogue (4c) with a chloramine solution gave the corresponding 4-sulfenamides (5a and 5c, respectively), which on selective oxidation with m-chloroperoxybenzoic acid (MCPBA) gave the respective diastereomeric 2-amino-7-β-D-ribofuranosylpyrrolopyrimidine-4-sulfinamide (7-deazasulfinosine, 6a) and its 2'-deoxy derivative (6c).A similar amination of 7-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolopyrimidine-4(3H)-thione (4b) gave the corresponding 4-sulfenamide derivative (5b).Oxidation of 5b with 1 molar equiv of MCPBA furnished (R,S)-7-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolopyrimidine-4-sulfinamide (6b), whereas use of excess of MCPBA afforded the corresponding sulfonamide derivative (7b).Treatment of 3-deaza-6-thioguanosine (8) with a chloramine solution gave 3-deazasulfenosine (6-amino-1-β-D-ribofuranosylimidazopyridine-4-sulfenamide, 9).Controlled oxidation of 9 with MCPBA afforded 3-deazasulfinosine (10).As gauged by increases in the mean postinoculation life spans of L1210 inoculated mice, none of these nucleosides exhibited biologically significant activity (T/C 125).Even so, antileukemic activity appeared to be influenced, albeit not uniformly, by structural modifications in the base and carbohydrate moieties of sulfenosine and sulfinosine.Thus, while several of the compounds were lacking in cytotoxic activity, eight others (4c, 5a, 5c, 6a, 6b, 7b, 9, and 10) were estimated to have reduced body burdens of viable L1210 cells by 16-77percent.

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