123004-74-0

Basic information

• Product Name: (2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester
• Synonyms: (2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester;(R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester;tert-butyl (2R)-4-bromo-2-{[(tert-butoxy)carbonyl]amino}butanoate
• CAS NO: 123004-74-0
• Molecular Formula: C₁₃H₂₄BrNO₄
• Molecular Weight: 338.23796
• Mol File: 123004-74-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 390.3±37.0 °C(Predicted)
• Appearance: /
• Density: 1.240
• PKA: 10.84±0.46(Predicted)
• CAS DataBase Reference: (2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester(123004-74-0)
• EPA Substance Registry System: (2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester(123004-74-0)

Safety Data

• Hazardous Substances Data: 123004-74-0(Hazardous Substances Data)

Usage

General Description

(2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester is a chemical compound that consists of a butanoic acid with a tert-butoxy carbonyl amino group and a bromo substituent on the 4th carbon. It also contains a tert-butyl ester group. (2R)-4-Bromo-2-[[(tert-butoxy)carbonyl]amino]butanoic acid tert-butyl ester is commonly used in the field of organic chemistry as a reagent or intermediate in chemical synthesis. It is important to handle this compound with care, as it can be hazardous if not used properly. Additionally, proper safety precautions should be taken when handling and storing this chemical.

Upstream product

• 77004-75-2 (3R)-4-tert-butoxy-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid 
• 110207-49-3 tert-butyl D-N-(tert-butoxycarbonyl)homoserinate 

Downstream Products

• 123004-79-5 D-N-(tert-butoxycarbonyl)-2-<4--3-(tert-butoxycarbonyl)propoxy>phenyl>glycine 
• 123004-75-1 D-N-(benzyloxycarbonyl)-2-<4--3-(tert-butoxycarbonyl)propoxy>phenyl>glycine 
• 1407507-34-9 di-tert-butyl (5R)-2-[4-(benzyloxy)benzyl]-2-(benzyloxycarbonyl)-5-[(tert-butoxy-carbonyl)amino]hexanedioate 
• 1407506-29-9 di-tert-butyl (2R)-2-[(tert-butoxycarbonyl)amino]-5-{4-[2-(tosyloxy)ethoxy]benzyl}-hexanedioate 
• 1407507-33-8 di-tert-butyl (5R)-2-(benzyloxycarbonyl)-5-[(tert-butoxycarbonyl)amino]hexane-dioate 
• 1407507-21-4 Di-tert-butyl (2R)-2-[(tert-butoxycarbonyl)amino]-5-(4-hydroxybenzyl)hexane-dioate 
• 110269-45-9 di-tert-butyl N-(tert-butoxycarbonyl)nocardicin A 
• 123004-77-3 (R)-4-[4-((R)-Amino-{(S)-1-[(R)-tert-butoxycarbonyl-(4-hydroxy-phenyl)-methyl]-2-oxo-azetidin-3-ylcarbamoyl}-methyl)-phenoxy]-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester; hydrochloride 
• 123004-76-2 (R)-4-[4-((R)-Benzyloxycarbonylamino-{(S)-1-[(R)-tert-butoxycarbonyl-(4-hydroxy-phenyl)-methyl]-2-oxo-azetidin-3-ylcarbamoyl}-methyl)-phenoxy]-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester 
• 123004-80-8 (R)-2-tert-Butoxycarbonylamino-4-[4-((R)-tert-butoxycarbonylamino-{(S)-1-[(R)-tert-butoxycarbonyl-(4-hydroxy-phenyl)-methyl]-2-oxo-azetidin-3-ylcarbamoyl}-methyl)-phenoxy]-butyric acid tert-butyl ester 

Relevant articles and documents

RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING

This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).

Total syntheses of (-)-nocardicins A-G: A biogenetic approach

The known nocardicins A-G have been synthesized, several for the first time, having geometric and stereoisomeric purities of a high order. The syntheses proceed through the central intermediacy of tert-butyl (-)-3-aminocardicinate (14), which has been pre