123016-47-7

Basic information

• Product Name: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• CAS NO: 123016-47-7
• Molecular Formula: C₁₉H₂₃FN₄O₃
• Molecular Weight: 374.4093
• Mol File: 123016-47-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 647.9°C at 760 mmHg
• Flash Point: 345.6°C
• Density: 1.391g/cm³
• Vapor Pressure: 1.14E-17mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(123016-47-7)
• EPA Substance Registry System: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(123016-47-7)

Safety Data

• Hazardous Substances Data: 123016-47-7(Hazardous Substances Data)

Upstream product

• 123016-57-9 5-amino-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 
• 21655-48-1 cis-2,6-dimethylpiperazine 
• 110871-86-8 sparfloxacin 

Relevant articles and documents

Defluorinated sparfloxacin as a new photoproduct identified by liquid chromatography coupled with UV detection and tandem mass spectrometry

Photodegradation of sparfloxacin was observed by means of high-pressure liquid chromatography with UV detection and liquid chromatography coupled with UV detection and tandem mass spectrometry (LC-MS/MS). Three products were detected. Comparison with an independently synthesized derivative of sparfloxacin revealed the structure of one product which is believed to be 8- desfluorosparfloxacin. The second product is likely to be formed by the splitting off of a fluorine and a cyclopropyl ring. Thus, photodefluorination of quinolone antibacterial agents is found and proved for the first time by LC-MS/MS.