123018-62-2

Basic information

• Product Name: 4,4-DI-N-PROPYLCYCLOHEXANONE
• Synonyms: 4,4-DIPROPYLCYCLOHEXAN-1-ONE;4,4-DIPROPYLCYCLOHEXANONE;4,4-DI-N-PROPYLCYCLOHEXANONE;4-DIPROPYLCYCLOHEXANONE
• CAS NO: 123018-62-2
• Molecular Formula: C₁₂H₂₂O
• Molecular Weight: 182.3
• Product Categories: Miscellaneous Reagents;Ring Systems;Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 123018-62-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 57-60°C/0.5 mm
• Flash Point: 95.6°C
• Appearance: /
• Density: 0.87g/cm³
• Vapor Pressure: 0.027mmHg at 25°C
• Refractive Index: 1.443
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate
• CAS DataBase Reference: 4,4-DI-N-PROPYLCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DI-N-PROPYLCYCLOHEXANONE(123018-62-2)
• EPA Substance Registry System: 4,4-DI-N-PROPYLCYCLOHEXANONE(123018-62-2)

Safety Data

• Hazardous Substances Data: 123018-62-2(Hazardous Substances Data)

Usage

Description

4,4-Di-N-propylcyclohexanone is a clear, colorless liquid with unique chemical properties that make it a valuable compound in the pharmaceutical industry. It is primarily utilized in the synthesis of N-substituted phenylacetamide derivatives, which are known for their therapeutic effects on pain and inflammation.

Uses

Used in Pharmaceutical Industry:
4,4-Di-N-propylcyclohexanone is used as a key intermediate compound for the preparation of N-substituted phenylacetamide derivatives. These derivatives serve as therapeutic agents for the treatment of pain and inflammation, making them essential in the development of medications aimed at alleviating these conditions.

InChI:InChI=1/C12H22O/c1-3-7-12(8-4-2)9-5-11(13)6-10-12/h3-10H2,1-2H3

Upstream product

• 60729-41-1 4,4-dipropylcyclohex-2-en-1-one 

Downstream Products

• 130065-93-9 ethyl α-cyano-α-(4,4-dipropylcyclohexylidene)acetate 
• 913747-65-6 4,4-dipropylcyclohexanoneoxime 
• 1314090-60-2 N-(4,4-dipropyl-cyclohexylidene)-N'-pyridin-4-ylhydrazine 
• 123018-48-4 SKandF 106610 
• 123018-47-3 atiprimod 
• 123018-34-8 N,N-dimethyl-8,8-dipropyl-2-azaspiro [4,5] decane-2-propanamine dihydrochloride 
• 948552-26-9 Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester 
• 130065-94-0 4,4-dipropyl-1-carboxycyclohexane-1-acetic acid 
• 123018-68-8 (1-Carboxymethyl-4,4-dipropyl-cyclohexyl)-acetic acid 
• 123018-64-4 4,4-dipropyl-1-carboxycyclohexane-1-acetic acid anhydride 

Relevant articles and documents

N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

A compound represented by the formula: (I) wherein R1 represents a methoxy group, a hydroxyl group or a hydrogen atom; R2 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkylcarbonyl group or an arylcarbonyl group; and D represents a group represented by the formula (A), (B) or (C) below. (A) (B) (C) This compound is useful as a therapeutic agent for a pain or inflammation induced by any one of various morbid conditions such as neuropathic pain, rheumatoid arthritis and osteoarthritis.

Immunomodulatory azaspiranes

A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and an effective amount of an azaspirane derivative, a method of treating an animal in need of immunomodulation which comprises administering to such animal an effective amount of an azaspirane derivative, and certain azaspirane derivatives.