123064-91-5

Basic information

• Product Name: 6-chloro-1-methyl-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline-7,8-dione
• Synonyms: Pyrrolo(4,3,2-de)quinoline-7,8-dione, 6-chloro-1,3,4,5-tetrahydro-1-methyl-; Pyrrolo[4,3,2-de]quinoline-7,8-dione, 6-chloro-1,3,4,5-tetrahydro-1-methyl-
• CAS NO: 123064-91-5
• Molecular Formula: C₁₁H₉ClN₂O₂
• Molecular Weight: 236.6544
• Mol File: 123064-91-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 450.3°C at 760 mmHg
• Flash Point: 226.1°C
• Density: 1.65g/cm³
• Vapor Pressure: 2.68E-08mmHg at 25°C
• Refractive Index: 1.76
• CAS DataBase Reference: 6-chloro-1-methyl-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline-7,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-1-methyl-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline-7,8-dione(123064-91-5)
• EPA Substance Registry System: 6-chloro-1-methyl-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline-7,8-dione(123064-91-5)

Safety Data

• Hazardous Substances Data: 123064-91-5(Hazardous Substances Data)

Upstream product

• 4770-06-3 4-nitroindole-3-acetonitrile 
• 169901-39-7 6-Chloro-1-methyl-1,3,4,5-tetrahydro-pyrrolo[4,3,2-de]quinoline 
• 90946-00-2 4-aminoindole-3-acetonitrile 
• 175792-34-4 8-chloro-6,7-dimethoxy-4-(dimethoxymethyl)-5-nitroquinoline 
• 175792-32-2 6-chloro-1,5-diformyl-1,3,4,5-tetrahydro-7,8-dimethoxypyrrolo<4,3,2-de>quinoline 
• 175792-33-3 6-chloro-5-formyl-1,3,4,5-tetrahydro-7,8-dimethoxy-1-methylpyrrolo<4,3,2-de>quinoline 
• 175792-35-5 6-chloro-5-formyl-1,3,4,5-tetrahydro-7,8-dimethoxypyrrolo<4,3,2-de>quinoline 
• 184957-93-5 5-amino-8-chloro-1,2,3,4-tetrahydro-6,7-dimethoxy-4-(dimethoxymethyl)quinoline 
• 175792-30-0 8-chloro-4-formyl-6,7-dimethoxy-5-nitroquinoline 
• 175792-29-7 8-chloro-6,7-dimethoxy-4-methyl-5-nitroquinoline 
• 6315-89-5 3,4-dimethoxyaniline 
• 159394-50-0 6,7-dimethoxy-4-methyl-5-nitroquinoline 
• 105908-35-8 6,7-dimethoxy-4-methylquinoline 
• 138770-77-1 6-chloro-7,8-dimethoxy-1-methyl-1,3,4,5-tetrahydropyrrolo<4,3,2-de>quinoline 

Downstream Products

• 138683-68-8 damirone B 

Relevant articles and documents

Total synthesis of makaluvamine A/D, damirone B, batzelline C, makaluvone, and isobatzelline C featuring one-pot benzyne-mediated cyclization- functionalization

Total synthesis of pyrroloquinoline alkaloids, such as makaluvamine A/D, damirone B, batzelline C, makaluvone, and isobatzelline C, was achieved featuring a one-pot benzyne-mediated cyclization-functionalization reaction. The synthetic utility was demonstrated by the construction of the common pyrrolo[4,3,2-de]quinoline skeleton.

Simple Total Syntheses of Marine Alkaloids, Batzelline C, Isobatzelline C, Damirone A, and Makaluvamine A

Batzelline C and isobatzelline C were synthesized in eight (or nine)steps from indole-3-carboxaldehyde.Syntheses of damirone A and makaluvamine A are also reported.

Total Syntheses of Batzelline C and Isobatzelline C, the Novel Pyrroloquinoline Alkaloids Isolated from the Marine Sponge Batzella Sp.

Total syntheses of batzelline C and isobatzelline C, two chlorine-containing alkaloids have been successfully accomplished employing the tricyclic indole derivative as a key intermediate.