123068-64-4

Upstream product

• 31252-42-3 4-benzylpyperidine 
• 67729-36-6 Boc-Phe-O-COO-isoBu 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Downstream Products

• 123068-87-1 H-L-Phe-BPP*HCl 
• 123068-58-6 Suc-Phe-BPP 
• 123068-59-7 Suc-Leu-Phe-BPP 
• 123068-85-9 H-L-Leu-L-Phe-BPP*HCl 
• 112259-73-1 Suc-L-Tyr-L-Leu-L-Phe-BPP 
• 123068-74-6 Boc-L-Tyr-L-Leu-L-Phe-BPP 
• 123068-84-8 H-L-Tyr-L-Leu-L-Phe-BPP*HCl 
• 123068-69-9 Boc-L-Leu-L-Phe-BPP 

Relevant academic research and scientific papers

NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS

The invention relates to novel bis-amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.

NOVEL BIS-AMIDES AS ANTIMALARIAL AGENTS

The invention relates to novel bis-amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.

Highly enantio- and diastereoselective synthesis of α- trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst

The first enantioselective Michael addition of α-cyanoketones to α,β-unsaturated trifluoromethyl ketones using a novel piperazine-thiourea catalyst was described. The resulting α- trifluoromethyldihydropyrans were obtained in high yields and with up to 95