123100-71-0

Upstream product

• 116724-98-2 5-((allylthio)methyl)-2-furfural 

Downstream Products

• 96194-71-7 (1S,5R,7S)-7-Benzyloxymethyl-10-oxa-3-thia-tricyclo[5.2.1.0^1,5]dec-8-ene 
• 123100-72-1 (1S,5R,7S)-7-(2-Bromo-benzyloxymethyl)-10-oxa-3-thia-tricyclo[5.2.1.0^1,5]dec-8-ene 

Relevant academic research and scientific papers

Scope of Tandem Cycloaddition/Radical Cyclization Methodology

Tandem cycloaddition/radical cyclization is an effective strategy for the rapid assembly of a wide variety of ring systems.To set up the reagents for this sequence, it is necessary to include a potential radical site in one of the two cycloaddition partners, located at an appropriate distance from a new double bond that will be formed in the cycloaddition step.Examples in which the cycloaddition step is or and in which the radical cyclization creates 5-, 6-, or 7-membered rings are described.Examples of the tandem methodology carried out in a completely intramolecular mode are also described.