123101-54-2Relevant academic research and scientific papers
ACCELERATION OF THE CONJUGATE ADDITION OF Ti "ATE" ENOLATES VIA LEWIS ACID CATALYSIS.
Bernardi, Anna,Cavicchioli, Marcello,Scolastico, Carlo
, p. 10913 - 10916 (2007/10/02)
The conjugate addition of Ti "ate" complexes of ketone enolates to α,β-unsaturated ketones can be accelerated by activating the substrate via complexation with t-BuMe2SiCl or trityl triflate.
Stereoselective Michael additions of titanium "ate" complexes of ketone and ester enolates
Bernardi, Anna,Dotti, Pierfranco,Poli, Giovanni,Scolastico, Carlo
, p. 5597 - 5606 (2007/10/02)
The conjugate addition of Ti "ate" complexes of ketone and ester enolates to α,β-unsaturated carbonyl compounds was studied. The reaction was found to be highly regio- and stereoselective. Compared to the lithium enolates, ketone enolate Ti complexes show
Stereochemistry of the Michael Addition of Ester and Ketone Enolates to α,β-Unsaturated Ketones
Oare, David A.,Heathcock, Clayton H.
, p. 157 - 172 (2007/10/02)
The stereo- and regiochemistry of addition of the enolates of ketones and esters to α,β-unsaturated ketones has been studied.There is a strong correlation between the enolate geometry and adduct stereostructure, with E enolates forming syn products and Z
INFLUENCE OF ENOLATE GEOMETRY ON THE STEREOCHEMISTRY OF MICHAEL ADDITIONS OF KETONE ENOLATES TO α, β-UNSATURATED KETONES
Oare, David A.,Heathcock, Clayton H.
, p. 6169 - 6172 (2007/10/02)
Preformed lithium enolates of ketones react with acyclic α,β-unsaturated ketones to give 1,5-diketones in good chemical yields.A strong correlation exists between enolate geometry and product stereochemistry; enolates having the Z configuration provide anti addition products while E enolates usually provide the syn diastereomers.
