1231169-92-8

Basic information

• Product Name: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(4-methylphenyl)methyl]butanoate
• CAS NO: 1231169-92-8
• Molecular Weight: 435.65
• Mol File: 1231169-92-8.mol

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(4-methylphenyl)methyl]butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(4-methylphenyl)methyl]butanoate(1231169-92-8)
• EPA Substance Registry System: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(4-methylphenyl)methyl]butanoate(1231169-92-8)

Safety Data

• Hazardous Substances Data: 1231169-92-8(Hazardous Substances Data)

Upstream product

• 24431-15-0 N-benzyl-p-tolylmethanimine 
• 6070-14-0 (-)-menthyl butyrate 

Relevant articles and documents

TiCl4 promoted menthyl ester chiral auxiliary mediated synthesis of chiral syn-β-amino esters and applications of a representative syn-β-amino ester

β-Amino esters were obtained in up to 78% yield with 72:28-96:4 diastereomeric ratios by the reaction of the chiral titanium enolate of menthyl esters, prepared using the TiCl4/Et3N reagent system with prochiral imines. A representative syn-β-amino ester derivative has been used for the resolution of racemic mandelic acid to obtain a sample with >99% ee in a single step. A representative syn-β-amino ester was converted to the corresponding N-deprotected amino ester using the Pd-C/HCOOH reagent system, and then to the corresponding β-amino acid using the glacial CH3COOH/HCl reagent system, and to the corresponding β-lactam derivative with partial epimerization by the reaction using C2H5MgBr.