1231192-27-0

Basic information

• Product Name: 3-[4-(4-bromophenyl)-1H-1,2,3-triazol-1-yl]-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
• Synonyms: 3-[4-(4-bromophenyl)-1H-1,2,3-triazol-1-yl]-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
• CAS NO: 1231192-27-0
• Molecular Weight: 483.263
• Mol File: 1231192-27-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[4-(4-bromophenyl)-1H-1,2,3-triazol-1-yl]-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(4-bromophenyl)-1H-1,2,3-triazol-1-yl]-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one(1231192-27-0)
• EPA Substance Registry System: 3-[4-(4-bromophenyl)-1H-1,2,3-triazol-1-yl]-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one(1231192-27-0)

Safety Data

• Hazardous Substances Data: 1231192-27-0(Hazardous Substances Data)

Upstream product

• 6226-25-1 2,2,2-trifluoroethyl trifluoromethanesulphonate 
• 1231192-62-3 3-[4-(4-bromophenyl)-1H-1,2,3-triazol-1-yl]-6-fluoro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 1231191-61-9 3-azido-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 

Downstream Products

• 1231190-97-8 6-fluoro-3-{4-[4-(pyridin-4-ylamino)phenyl]-1H-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 1231190-35-4 6-fluoro-3-(4-{4-[(2-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 1231191-58-4 6-fluoro-1-(2,2,2-trifluoroethyl)-3-(4-{4-[2-(trifluoromethyl)pyridin-4-yl]phenyl}-1H-1,2,3-triazol-1-yl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 

Relevant articles and documents

TRIAZOLE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE

According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of A?42 and hence are useful in treatment of Alzheimer's disease and related conditions.