1231713-81-7Relevant articles and documents
RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF
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Paragraph 0142, (2021/09/16)
Provided are a Rho kinase inhibitor, a method for preparing same and the uses thereof. The Rho kinase inhibitor designates a compound of Formula I, a stereoisomer thereof or pharmaceutically acceptable salt thereof. The Rho kinase inhibitor promotes endothelial cells and endothelin expression, prostenin expression, and vascular factors NO synthesis and secretion, has a promoting effect on proprostin expression independently of the doses used, shows lower toxicity, while being safer.
TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
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Paragraph 1009; 1010, (2016/10/27)
The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D]pyrimidine compounds and pharmaceutical compositions which, among other things, modulate toll-like receptors (e.g. TLR-8), and methods of making and using them.
