123172-79-2Relevant academic research and scientific papers
SYNTHESIS OF OPTICALLY-ACTIVE EPHEDRINE-LIKE COMPOUNDS via COORDINATED DIASTEREOSELECTIVE FRIEDEL-CRAFTS ALKYLATION OF PHENOL SYSTEMS
Bigi, Franca,Casnati, Giuseppe,Sartori, Giovanni,Araldi, Gianluca
, p. 413 - 419 (2007/10/02)
The first direct diastereoselective synthesis of ephedrine-like compounds has been performed by hydroxyalkylation of metal phenolates with N-protected α-amino aldehydes: β-amino-ortho-hydroxybenzyl alcohols were obtained with good to excellent diastereose
HIGHLY REGIO- AND DIASTEREOSELECTIVE FRIEDEL-CRAFTS ALKYLATION OF PHENOLS WITH α-AMINO ALDEHYDES. SYNTHESIS OF OPTICALLY ACTIVE EPHEDRINE-LIKE COMPOUNDS
Bigi, Franca,Casnati, Giuseppe,Sartori, Giovanni,Araldi, Gianluca,Bocelli, Gabriele
, p. 1121 - 1124 (2007/10/02)
The first direct diastereoselective synthesis of ephedrine-like compounds has been achieved by alkylation of metal phenolates with N-tert-butoxycarbonyl-α-amino aldehydes; β-amino-ortho-hydroxybenzyl alcohols were obtained with good to excellent diastereoselection.
