123186-07-2Relevant academic research and scientific papers
Preparation of Seven-Membered-Ring Cyclic Ethers and 3-Alkylidenetetrahydropyrans from the Cyclization of Oxonium Cations Derived from Unsubstituted and Silicon-Containing 4-Alken-1-ols
Castaneda, Armando,Kucera, David J.,Overman, Larry E.
, p. 5695 - 5707 (2007/10/02)
Lewis acid promoted cyclization of mixed acetals derived from 4-alken-1-ols provides direct access to seven- or six-membered cyclic ethers.Ring size is determined primarily by the electronic bias of the alkene participant.Of particular significance are (a
