1232169-22-0Relevant articles and documents
Screening of polymeric supports and enzymes for the development of an endo enzyme cleavable linker
Chiva, Ana,Williams, David E.,Tabor, Alethea B.,Hailes, Helen C.
, p. 2720 - 2723 (2010)
Several polymeric supports possessing an ester moiety were prepared and a range of enzymes was investigated to hydrolyse the ester linkage and release a signalling group into solution for applications in immunoassays. Pseudomonas lipases were found to most readily cleave the solution-phase analogue and this observation translated well to the corresponding polymeric supports, where the most effective were PEGA resins and the LPOS support PEG-6000.