123239-02-1

Upstream product

• 106942-45-4 N-<3,3,3-trifluoro-2-oxo-1-(2-methylethyl)propyl>benzamide 
• 38675-10-4 N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl-L-proline 
• 106942-36-3 4-Isopropyl-2-phenyl-4-(2,2,2-trifluoro-acetyl)-4H-oxazol-5-one 
• 106746-07-0 N-(3,3,3-trifluoro-2-hydroxy-1-(methylethyl)propyl)benzamide 
• 106746-09-2 3(RS)-amino-1,1,1-trifluoro-2(RS)-hydroxy-4-methylpentane hydrochloride 

Downstream Products

• 123206-20-2 N-<(1,1-dimethylethoxy)carbonyl>-D-phenylalanyl-N-<3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl>-L-prolinamide 
• 123206-21-3 D-phenylalanyl-N-<3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl>-L-prolinamide hydrochloride 
• 123206-22-4 N-(4-methoxy-1,4-dioxobutyl)-D-phenylalanyl-N-<3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl>-L-prolinamide 

Relevant academic research and scientific papers

Synthesis of peptidyl fluoromethyl ketones and peptidyl α-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G

Comparison of MeO-Suc-Val-Pro-Phe-CO2Me (29) and MeO-Suc-Ala-Ala-Pro-Phe-CO2Me (25) with their corresponding trifluoromethyl ketones 9a and 9b, respectively, in rat and human neutrophil cathepsin G assays showed the α-keto esters to