123239-69-0Relevant academic research and scientific papers
Ruthenium-catalyzed coupling of α-carbonyl phosphoniums with sulfoxonium ylidesviaC-H activation/Wittig reaction sequences
Chen, Tian,Ding, Zhiqiang,Guan, Yuqiu,Zhang, Ruike,Yao, Jinzhong,Chen, Zhangpei
supporting information, p. 2665 - 2668 (2021/03/16)
A Ru(ii)-catalyzed coupling of various α-carbonyl phosphoniums with sulfoxonium ylides has been realized for the facile synthesis of 1-naphthols in good to excellent yields. This oxidant-free transformation proceeds through Ru-catalyzed C-H activation of phosphoniums, Ru-carbene insertion, and intramolecular Wittig reaction processes.
General Preparation of 3-Alkyl-1-Naphthols
Makra, Ferenc,Rohloff, John C.,Muehldorf, A. V.,Link, John O.
, p. 6815 - 6818 (2007/10/02)
Potassium enolates derived from readily available o-alkynylacetophenones undergo intramolecular cycloaromatization on heating to afford 3-alkyl-1-naphthols in good yields. - Key words: Cycloaromatization, enynone, ynenone, 3-alkyl-1-naphthol.
2-Substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity
Batt,Maynard,Petraitis,Shaw,Galbraith,Harris
, p. 360 - 370 (2007/10/02)
The synthesis, biological evaluation, and structure-activity relationships of a series of 1-naphthols bearing carbon substituents at the 2-position are described. These compounds are potent inhibitors of the 5-lipoxygenase from RBL-1 cells and also inhibi
