123251-08-1

Basic information

• Product Name: [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-Methoxy-4H-furo[3,2-c]pyran-2(6H)-one
• Synonyms: [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-Methoxy-4H-furo[3,2-c]pyran-2(6H)-one
• CAS NO: 123251-08-1
• Molecular Formula: C8H10O5
• Molecular Weight: 186.162
• Product Categories: Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 123251-08-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 134-136 °C
• Boiling Point: 462.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.40±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 12.44±0.40(Predicted)
• CAS DataBase Reference: [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-Methoxy-4H-furo[3,2-c]pyran-2(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-Methoxy-4H-furo[3,2-c]pyran-2(6H)-one(123251-08-1)
• EPA Substance Registry System: [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-Methoxy-4H-furo[3,2-c]pyran-2(6H)-one(123251-08-1)

Safety Data

• Hazardous Substances Data: 123251-08-1(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

Uses

Patulin intermediate.

Upstream product

• 123251-06-9 methyl 2-deoxy-3,4-O-isopropylidene-2-C-β-L-erythro-pentopyranoside 

Downstream Products

• 123251-09-2 (S)-O-methylpatulin 

Relevant articles and documents

Ylidenebutenolide Mycotoxins. Concise Syntheses of Patulin and Neopatulin from Carbohydrate Precursors

Conversion of arabinose 10 to the protected ketone 13 followed by Wittig condensation to 14, acidcatalysed cyclisation (to lactone 16), dehydration and deprotection provides a brief synthesis of the mycotoxic substance patulin 1, which is produced by Penicillium and Aspergillus spp.In a similar manner, the biogenetic precursor to patulin, neopatulin 8, is synthesized from lyxose 25 via the key intermediates 24, 28 and 30.