1233142-73-8Relevant academic research and scientific papers
Synthesis of azaspirocycles and their evaluation in drug discovery
Burkhard, Johannes A.,Wagner, Bjoern,Fischer, Holger,Schuler, Franz,Mueller, Klaus,Carreira, Erick M.
supporting information; experimental part, p. 3524 - 3527 (2010/08/06)
(Figure Presented). Make It spirol Readily synthesized heteroatom- substituted spiro[3.3]heptanes generally show higher aqueous solubility than their cyclohexane analogues, and show a trend towards higher metabolic stability. The novel framework can be mo
