1233145-49-7 Usage
Molecular structure
1-Piperidineacetamide, 4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]is a complex organic compound with multiple aromatic rings, piperidine, acetamide, and various functional groups.
Aromatic rings
The compound contains multiple aromatic rings, including a phenyl ring and a pyrrolopyrrolotriazine ring, which may contribute to its biological activity.
Functional groups
The presence of methoxy and amino groups in the compound suggests potential interactions with biological targets, such as receptors or enzymes.
Biological activity
The compound's structure suggests potential biological activity, possibly as a receptor modulator or enzyme inhibitor, which could be useful in drug development.
Pharmaceutical applications
Due to its complex structure and potential biological activity, 1-Piperidineacetamide, 4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]may have potential pharmaceutical applications, although further research and testing are required to determine its exact pharmacological properties and uses.
Receptor modulator
The compound may act as a receptor modulator, binding to specific receptors in the body and altering their activity, which could have therapeutic effects.
Enzyme inhibitor
The compound may also function as an enzyme inhibitor, blocking the activity of specific enzymes and potentially leading to therapeutic benefits.
Further research and testing
To fully understand the pharmacological properties and potential uses of 1-Piperidineacetamide, 4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]-, further research and testing are necessary. This may include in vitro and in vivo studies to evaluate its efficacy, safety, and potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1233145-49-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,3,1,4 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1233145-49:
(9*1)+(8*2)+(7*3)+(6*3)+(5*1)+(4*4)+(3*5)+(2*4)+(1*9)=117
117 % 10 = 7
So 1233145-49-7 is a valid CAS Registry Number.
1233145-49-7Relevant articles and documents
Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f ][1,2,4]triazines: Identification of orally bioavailable, efficacious ALK inhibitors
Mesaros, Eugen F.,Thieu, Tho V.,Wells, Gregory J.,Zificsak, Craig A.,Wagner, Jason C.,Breslin, Henry J.,Tripathy, Rabindranath,Diebold, James L.,McHugh, Robert J.,Wohler, Ashley T.,Quail, Matthew R.,Wan, Weihua,Lu, Lihui,Huang, Zeqi,Albom, Mark S.,Angeles, Thelma S.,Wells-Knecht, Kevin J.,Aimone, Lisa D.,Cheng, Mangeng,Ator, Mark A.,Ott, Gregory R.,Dorsey, Bruce D.
, p. 115 - 125 (2012/03/11)
Chemical strategies to mitigate cytochrome P450-mediated bioactivation of novel 2,7-disubstituted pyrrolo[2,1-f][1,2,4]triazine ALK inhibitors are described along with synthesis and biological activity. Piperidine-derived analogues showing minimal microsomal reactive metabolite formation were discovered. Potent, selective, and metabolically stable ALK inhibitors from this class were identified, and an orally bioavailable compound (32) with antitumor efficacy in ALK-driven xenografts in mouse models was extensively characterized.
