123316-47-2Relevant academic research and scientific papers
STERICALLY SCREENED HALOGENOCYCLOBUTANONES. IV. FAVORSKY REARRANGEMENT IN CYCLOPROPYL-SUBSTITUTED 2-CHLOROCYCLOBUTANONES
Donskaya, N. A.,Bessmertnikh, A. G.,Shabarov, Yu. S.
, p. 295 - 301 (2007/10/02)
The Favorsky rearrangement of cyclopropyl-substituted 2-chlorocyclobutanones and 5-chlorospirohexan-4-ones by the action of potassium hydroxide leads to the respective carboxylic acids of the bicyclopropyl and spiropentane series.In the case of the unsymmetrically substituted chlorocylobutanones the rearrangement is nonstereospecific as a result of their ready enolization.
