123317-51-1 Usage
Chelating agent
The compound can chelate metal ions, particularly gadolinium, for use as contrast agents in magnetic resonance imaging (MRI).
Macrocyclic structure
The tetraazacyclododecane core provides a stable and rigid structure for binding metal ions.
Nitrobenzyl group
This functional group can be used for conjugation to other molecules, such as drugs or imaging agents.
Tetraacetic acid groups
These functional groups provide multiple binding sites for metal ions, enhancing the stability of the resulting complex.
Conjugation to drugs
The compound can be conjugated to drugs to improve their solubility and target them to specific tissues.
Biomedical and pharmaceutical applications
Due to its structure and properties, the compound has the potential for various applications in the biomedical and pharmaceutical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 123317-51-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,3,1 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 123317-51:
(8*1)+(7*2)+(6*3)+(5*3)+(4*1)+(3*7)+(2*5)+(1*1)=91
91 % 10 = 1
So 123317-51-1 is a valid CAS Registry Number.
123317-51-1Relevant articles and documents
A New Synthetic Route to 2-(p-Nitrobenzyl)-1,4,7,10-Tetraazacyclododecane
Garrity, Martha L.,Brown, Gilbert M.,Elbert, Jeffrey E.,Sachleben, Richard A.
, p. 5531 - 5534 (2007/10/02)
A new, general synthetic method for the title compound has been developed, based on the nitration of 2-benzyl-1,4,7,10-tetraazacyclododecane (64 percent yield), which provides higher yields and easier purification for scale-up than previously reported met
The Peptide Way to Macrocyclic Bifunctional Chelating Agents: Synthesis of 2-(p-Nitrobenzyl)-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic Acid and Study of Its Yttrium(III) Complex
Moi, Min K.,Meares, Claude F.,DeNardo, Sally J.
, p. 6266 - 6267 (2007/10/02)
It was shown that the 12-membered polyazamacrocycle is the favored target for binding trivalent yttrium.We have developed a new synthetic route to these macrocycles via peptide synthesis and intramolecular tosylamide ring closure.
