123318-81-0

Basic information

• Product Name: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purine-2,6-diamine
• Synonyms: 9-(2,3-dideoxy-2-fluoro-.beta.-threo-pentofuranosyl)-2,6-diaminopurine; 9-(2,3-dideoxy-2-fluoro-beta-threo-pentofuranosyl)-2,6-diaminopurine; 9H-Purine-2,6-diamine, 9-(2,3-dideoxy-2-fluoro-b-D-threo-pentofuranosyl)-
• CAS NO: 123318-81-0
• Molecular Formula: C₁₀H₁₃FN₆O₂
• Molecular Weight: 268.2476
• Mol File: 123318-81-0.mol

Chemical Properties

• Boiling Point: 656.4°C at 760 mmHg
• Flash Point: 350.8°C
• Density: 2.01g/cm³
• Vapor Pressure: 4E-18mmHg at 25°C
• Refractive Index: 1.859
• CAS DataBase Reference: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purine-2,6-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purine-2,6-diamine(123318-81-0)
• EPA Substance Registry System: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purine-2,6-diamine(123318-81-0)

Safety Data

• Hazardous Substances Data: 123318-81-0(Hazardous Substances Data)

Upstream product

• 127409-09-0 2-amino-6-chloro-9-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)-9H-purine 
• 156900-28-6 2,6-dichloro-9-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)-9H-purine 
• 136228-16-5 5-O-Benzoyl-2,3-dideoxy-2-fluoro-1-O-methyl-β-D-threo-pentofuranose 
• 136228-19-8 5-O-benzoyl-2,3-dideoxy-2-fluoro-α-D-arabinofuranosyl bromide 

Relevant articles and documents

2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides

A compound has the formula STR1 wherein R is selected from the group consisting of (C7 -C20)aroyl, (C6 -C20)aryl, aralkyl and alkylaryl, and (C1 -C10)alkyl-di(C6 -C20)aryl Si, R' is selected from the group consisting of (C1 -C10)alkyl, (C7 -C20)aroyl and (C2 -C12)acyl, all of which may be further substituted with O, S, N or alkyl, and R'" is selected from the group consisting of halogen, (C1 -C10)alkoxy, (C1 -C10)acyloxy, O-methane-sulfonyl and O-p-toluenesulfonyl. A composition of matter comprises 0.001 to 99.999 wt % of the above compound.

Chemistry and anti-HIV activity of 2'-β-fluoro-2',3'-dideoxyguanosine

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