1233193-55-9

Upstream product

• 1233193-56-0 C₄₇H₅₆O₃Si₂ 
• 1233193-54-8 3-(tert-butyl-diphenyI-silanyloxy)-2-trityloxymethyl-cyclo-pentanol 
• 1233193-50-4 3-(tert-butyl-diphenyl-silanyloxy)-2-trityloxymethyl-cyclo-pentanone 
• 1233193-52-6 2-((trityloxy)methyl)cyclopent-2-en-1-one 
• 1233193-51-5 (S)-2-((trityloxy)methyl)cyclopent-2-en-1-ol 
• 1233193-53-7 tert-butyl-diphenyl-(2-trityloxymethyl-cycIo-2-pentenyloxy)-silane 

Downstream Products

• 1233193-58-2 (1R,3R,4S)-4-tert-butyldiphenylsilyloxy-3-(trityloxymethyl)-2-methylene-1-cyclopentanol 
• 142217-69-4 entecavir 
• 1233193-59-3 9-[4-(tert-butyl-diphenyl-silanyloxy)-2-methylene-3-trityloxymethyl-cyclopentyl]-6-chloro-9H-purine-2-yl amine 
• 1233193-60-6 [3-(2-amino-6-chloro-purine-9-yl)-5-(tert-butyl-diphenyl-silanyloxy)-2-methylene-cyclopentyl]-methanol 

Relevant academic research and scientific papers

NOVEL INTERMEDIATE AND PROCESS FOR PREPARING ENTECAVIR USING SAME

The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.

NOVEL INTERMEDIATE AND PROCESS FOR PREPARING ENTECAVIR USING SAME

The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4,β]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.