123320-77-4Relevant academic research and scientific papers
Sulphonamide Nitrogen-containing, Nitrogen-protected Amino Acids interacting with the Cd2+ Ion. A Cadmium-113 Nuclear Magnetic Resonance and Potentiometric Study. X-Ray Diffraction of
Gavioli, Giovanna Battistuzzi,Menabue, Ledi,Saladini, Monica,Sola, Marco,Corradi, Anna Bonamartini,Battaglia, Luigi P.
, p. 1345 - 1350 (2007/10/02)
α-Alanine and β-alanine, N-protected by a tosyl (toluene-p-sulphonyl) group, bind Cd2+ acting initially as a simple carboxylate at low pH, and, at increasing pH, as N,O-bidentate ligands, through the carboxylic oxygen and the deprotonated amide nitrogen atoms.In the latter case they give rise to five- and six-membered ring chelate species, respectively.Cadmium-113 n.m.r. and potentiometric measurements reveal that the stability of the complexes is almost unaffected by the chelate ring size.The five-membered ring chelate species has a more deshielded chemical shift and only a slightly greater stability than the six-membered species.The crystal and molecular structures of the (ts-β-alaO = N-tosyl-β-alaninate monoanion) complex have been solved.Crystal data are: monoclinic, space group P21/c, a = 14.956(6), b = 5.472(2), c = 16.860(7) Angstroem, β = 107.36(3) deg, Z = 2, and R = 0.039 for 1 635 reflections.The amino acid molecule binds through the unidentate carboxylate group and the structures consists of discrete units in which the Cd2+ exhibits a nearly regular octahedral geometry.
