1233239-42-3

Basic information

• Product Name: 4-phenyl-1-(thiophen-2-yl)-1H-1,2,3-triazole
• Synonyms: 4-phenyl-1-(thiophen-2-yl)-1H-1,2,3-triazole
• CAS NO: 1233239-42-3
• Molecular Weight: 227.29
• Mol File: 1233239-42-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-phenyl-1-(thiophen-2-yl)-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-1-(thiophen-2-yl)-1H-1,2,3-triazole(1233239-42-3)
• EPA Substance Registry System: 4-phenyl-1-(thiophen-2-yl)-1H-1,2,3-triazole(1233239-42-3)

Safety Data

• Hazardous Substances Data: 1233239-42-3(Hazardous Substances Data)

Upstream product

• 6165-68-0 thiophene boronic acid 
• 536-74-3 phenylacetylene 
• 1026668-29-0 bis(2-thiophenyl)iodonium tosylate 
• 1003-09-4 2-bromothiophene 
• 66768-58-9 2-azidothiophene 

Relevant articles and documents

Immobilization of vitamin B1 on the magnetic dialdehyde starch as an efficient carbene-type support for the copper complexation and its catalytic activity examination

Since the starch biopolymer is an available and inexpensive matrix with modifiable functionality and stabilization capability for metal ions, in this report, we oxidized it to dialdehyde form for the further functionalization with vitamin B1 as a green σ-donor and π-acceptor carbene type ligand. Immobilization of vitamin B1 on this biopolymer was done through imine bond formation between NH2 groups of aminopyrimidine segment of vitamin B1 and aldehyde functional groups of starch oxide. Thiazolium heterocycle part in this biomolecule provided a carbene type precursor for the metal complexation. After the magnetization process by using of Fe3O4 nanoparticles that lead to quick and facile magnetic separation and metal catalyst recycling, copper ions immobilized on the magnetic support (5.9 wt% Cu, 0.93 mmol/g). The prepared copper N-heterocyclic carbene complex (Fe3O4@DAS@VB1@CuCl nanocomposite) was characterized by FT-IR, SEM, EDX, XRD, VSM, TGA and ICP-OES analysis and then its catalytic activity investigated in azidonation of arylboronic acids and also one-pot coupling reaction of the synthesized aryl azides with phenylacetylene. 1,4-Diaryl 1,2,3-triazoles were obtained in excellent yields (≥90%) at proper reaction times (30–200 min). The magnetic catalyst was recovered by a magnetic field and reused in azidation reaction up to 7 cycle.

Ag2CO3-catalyzed cycloaddition of organic azides onto terminal alkynes: A green and sustainable protocol accelerated by aqueous micelles of CPyCl

Using catalytic amount of Ag2CO3 a simple, efficient and copper free green protocol has been developed to synthesize 1,4-disubstituted 1,2,3-triazoles regioselectively. Here, the cationic surfactant, cetylpyridinium chloride (CPyCl) in water provides a micellar media and accelerates the subsequent Ag(I)-catalysed azide-alkyne cycloaddition (AgAAC) reaction by increasing the concentration of reactants in the micellar pseudophase. Our method is found to be environmentally friendly from E-factor measurement. The surfactant, CPyCl is found to be nontoxic.

N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS

Provided herein are new N-,C-disubstituted azoles and derivatives thereof that exhibit nematicidal activity and are useful, for example, in methods for the control of unwanted nematodes.